Searchable abstracts of presentations at key conferences in endocrinology

ea0029p1285 | Paediatric endocrinology | ICEECE2012

ACTH and cortisol are differently associated with metabolic syndrome components in a large cohort of Caucasian obese children and adolescents

Ricotti R. , Prodam F. , Bellone S. , Walker G. , Parlamento S. , Savastio S. , Genoni G. , Agarla V. , Aimaretti G. , Bona G.

Introduction: Higher cortisol levels and, in particular, hyperactivity of the HPA axis might play a role in the development of MS at least in adults. Data on the pediatric age are scanty.Aim of our study was to evaluate ACTH and cortisol association with MS, its components, phenotypic parameters, family history of metabolic derangements in pediatric obesity.Methods: Cross-sectional study. 271 Caucasian overweight or obese children ...

ea0026p166 | Neuroendocrinology | ECE2011

Evaluation of insulin secretion and sensitivity and lipid profile in GH deficient children before and at the end of rhGH therapy

Prodam F , Savastio S , Bellone S , Balossini C , Ricotti R , Genoni G , Aimaretti G , Bona G

Introduction: A rise in serum insulin levels during GH therapy is reported. Insulin resistance is a risk factor for type 2 diabetes, atherosclerosis, dyslipidemia, and hypertension. Few data describe insulin secretion and lipids after the end of GH therapy.Subjects and methods: Aim of our study was to evaluate changes in insulin secretion, sensitivity and lipid profile in children with isolated GHD longitudinally followed during rhGH treatment. We measur...

ea0029p595 | Diabetes | ICEECE2012

Comparative incidence of type 1 diabetes mellitus in school-aged children between immigrated families and the background population living in Piedmont or in Morocco, 2005–2009: a role for vitamin D?

Savastio S. , Prodam F. , Perino A. , Balafrej A. , Monzani A. , Lera R. , Fontana F. , Cerutti F. , Bona G. , Cadario F.

Introduction: The aim was to compare the incidence of type 1 diabetes between immigrant Moroccan and Romanian children and background population in Piedmont, Italy, and between Moroccan children living in Italy and their counterpart in Morocco.Patients and methods: All new cases of type 1 diabetes aged 6–13 years in Piedmont and Morocco in 2005–2009 were retrieved by regional registries. Numbers of children regularly registered to primary and m...

ea0029p1284 | Paediatric endocrinology | ICEECE2012

Insulin secretion and sensitivity in GH deficient children at the end of rhGH therapy and after 1 year of follow-up: influences of d3GH receptor polymorphism on metabolic parameters

Agarla V. , Prodam F. , Savastio S. , Petri A. , Balossini C. , Ricotti R. , Genoni G. , Aimaretti G. , Bona G. , Bellone S.

Introduction: A rise in serum insulin levels during GH therapy is reported. Insulin resistance is a risk factor for type 2 diabetes, atherosclerosis, dyslipidemia, and hypertension. Few data describe insulin secretion and sensitivity after the end of GH therapy in children.Methods: Aim of our study was to evaluate changes in insulin secretion and sensitivity in 24 children with isolated GHD at 3 times: i) during the last year of therapy (T0); ii) 6 month...